Jan Serfontein and Schalk Brits have also been included in the match-23 for the first time this season.
A total of 28 players will travel to South America on Wednesday to play the Pumas at the Vélez Sarsfield on Saturday evening (SA time). The match-23 shows numerous changes from the side that lost to Argentina last weekend, many of them injury-enforced.
Kirchner takes over at fullback from the injured Willie le Roux; Jesse Kriel moves from wing to centre for Jean de Villiers, with Mvovo getting his third run of the season, in the No 14-jersey. Alberts replaces the injured Marcell Coetzee in what will be his first Test in more than a year.
“It’s great to have Victor and Willem back from their injuries and we’re all looking forward to going to Buenos Aires and improve on our performance from last weekend,” said Springbok coach Heyneke Meyer.
“A few more players in our enlarged squad will get opportunities this weekend and I’m excited to see what they can do in difficult circumstances, playing in front of a very noisy crowd against a strong side away from home.